Umdlavuza we-Pancreatic
Incazelo emfushane:
Umdlavuza we-pancreatic ungomunye womdlavuza obulala kakhulu othinta i-pancreas, isitho esitholakala ngemuva kwesisu. Kwenzeka lapho amangqamuzana angajwayelekile ku-pancreas eqala ukukhula ngokungalawuleki, akha isimila. Izigaba zokuqala zomdlavuza we-pancreatic ngokuvamile azibangeli zimpawu. Njengoba isimila sikhula, singadala izimpawu ezifana nobuhlungu besisu, ubuhlungu bomhlane, ukwehla kwesisindo, ukulahlekelwa yisifiso sokudla, kanye ne-jaundice. Lezi zimpawu zingabangelwa ezinye izimo futhi, ngakho-ke kubalulekile ukubona udokotela uma uhlangabezana nanoma yisiphi sazo.
Ukwelashwa okusebenza kahle kakhulu komdlavuza we-pancreatic kuncike esigabeni somdlavuza kanye nempilo yesiguli iyonke. Ukuhlinzwa kuyindlela eyinhloko yokwelapha umdlavuza we-pancreatic, okuhlanganisa nokuhlinzwa kwe-Whipple kanye nokuhlinzwa kwe-Distal, kodwa kungenzeka kuphela uma umdlavuza ungasakazekanga ngale kwe-pancreas. Njengamanje, amanye amasu amasha okuhlinzwa kanye nezinsimbi, njengokuhlinzwa okuncane okungavamile, ukuhlinzwa kwe-robotic kanye nobuchwepheshe bokuphrinta be-3D, nakho kusetshenziswa kabanzi ekwelapheni umdlavuza we-pancreatic ukuthuthukisa umphumela wokuhlinzwa kanye nezinga lokusinda kweziguli.
Ukwelashwa ngamakhemikhali kanye nokwelashwa ngemisebe nakho kungasetshenziswa ukwelapha umdlavuza we-pancreatic, kungaba wedwa noma kuhlanganiswe nokuhlinzwa. Eminyakeni yamuva nje, imithi emisha yokwelapha ngamakhemikhali, njenge-Navumab kanye ne-Paclitaxel, isetshenziswe kabanzi ekwelapheni umdlavuza we-pancreatic, okungathuthukisa kakhulu ukusebenza kahle kwe-chemotherapy kanye nezinga lokusinda kweziguli.
Ukwelashwa okuqondiwe kubhekisela ekusetshenzisweni kwemithi eqondiswe ezinhlosweni zesimila, njengezithibi zokukhula kwe-epidermal factor receptor kanye nezithibi zokukhula kwe-vascular endothelial factor receptor, ukuvimbela ukukhula nokusabalala kwesimila. Ukwelashwa okuqondiwe kungathuthukisa kakhulu ukusebenza kahle kanye nezinga lokusinda kweziguli ezinomdlavuza we-pancreatic.
Ukwelashwa nge-immunotherapy kubhekisela ekusetshenzisweni kwamandla esimiso somzimba sokuzivikela sesiguli ukuhlasela amangqamuzana omdlavuza, njengezithibi zokuhlola amasosha omzimba, ukwelashwa ngamaseli e-CAR-T njalo njalo. Ukwelashwa nge-immunotherapy kungathuthukisa amasosha omzimba eziguli, kuthuthukise ukusebenza kahle komdlavuza we-pancreatic kanye nezinga lokusinda kweziguli.
Umdlavuza we-pancreatic yisifo esibi kakhulu esingabangela izimpawu ezinzima futhi kungaba nzima ukwelapha. Kubalulekile ukubona udokotela uma uhlangabezana nanoma yiziphi izimpawu, njengoba ukutholakala kusenesikhathi kungathuthukisa amathuba okwelashwa okuphumelelayo.