Ngomhlaka-28 kuNhlolanja 2026, i-National Medical Products Administration (NMPA) yavuma ngokusemthethweni ukudayiswa kwe-JMKX001899 sulfate yokwelapha iziguli ezindala ezine-KRAS G12C-mutated advanced non-small cell lung cancer (NSCLC) ezithole okungenani ukwelashwa okukodwa kwangaphambilini kwesistimu.
I-JMKX001899 iyi-KRAS G12C inhibitor ekhetheke kakhulu futhi ngaphambilini ithole igama elithi “Breakthrough Therapy” elivela kwi-NMPA.
Imininingwane ebalulekile yezokwelapha iyakhuthaza:
- Izinga lokuphendula eliqondile (ORR) lifinyelele phezulu ku-55.2%
- Izinga lokusinda okuphelele kwezinyanga eziyi-12 (OS) lifinyelele ku-60.4%
Ngaphezu kwedatha enhle kakhulu yezinzuzo zokusinda, i-JMKX001899 iphinde ifeze ukuthuthukiswa okukhulu kokuhlangenwe nakho kwemithi yesiguli, isebenzisa uhlelo lokulinganisa olulula "kanye ngosuku, amaphilisi amabili isikhathi ngasinye," ngokubekezeleleka okuhle, ngaleyo ndlela ithuthukise ukuthobela kwesiguli imithi yesikhathi eside.
Njengamanje, izifundo zezokwelapha zalo muthi ziyaqhubeka nasezigulini ezinezimila eziqinile njengomdlavuza we-colorectal oqukethe izinguquko ze-KRAS G12C, okungenzeka ukuthi zizuzise izinhlobo eziningi zeziguli zomdlavuza esikhathini esizayo.
**Kungani ukhethe uMnyango Wezizwe Ngezizwe Wesibhedlela Se-Oncology saseBeijing South Region?**
- **Ubuchwepheshe Bezokwelapha Obusezingeni Eliphezulu:** Sihlala sazi ngentuthuko yakamuva yamazwe ngamazwe ekwelashweni komdlavuza futhi siphakathi kwabokuqala ukwethula imithi emisha kanye nokwelashwa, okuhlanganisa i-JMKX001899.
- **Ithimba Lochwepheshe Abahlukahlukene:** Ithimba lethu lokubonisana elihlanganisa ochwepheshe abanolwazi lwe-oncology, odokotela be-radiology, kanye nodokotela bezifo abakha izinhlelo zokwelapha ezenzelwe umuntu ngamunye.
- **Isevisi Yokuhlinzeka Ngayo Yonke Indawo:** Kusukela ekubonisaneni kokuqala kanye nokuhlolwa kofuzo kuya ekuthuthukisweni kohlelo lokwelashwa, isiqondiso semithi, kanye nokuphathwa kokulandelela, sinikeza izinsizakalo zezokwelapha ezingenazihibe, eziphelele.
- **Indawo Yokwelapha Yomhlaba Wonke:** Sihlonyiswe ngezikhungo zezokwelapha ezithuthukisiwe, sakha indawo yokuphulukisa efudumele nekhululekile futhi sihlonipha izidingo ezithile zeziguli ezivela ezizindeni zamasiko ahlukahlukene.
- **Izinsizakalo Zokusekela Ulimi:** Sinikeza izinsizakalo zokuhumusha izilimi eziningi ukuze sisuse izithiyo zokuxhumana futhi siqinisekise ukuxhumana okunembile phakathi kodokotela neziguli.
**Xhumana Nathi Manje Ukuze Uthole Izinketho Zokwelapha Ezisezingeni Eliphezulu**
Uma wena noma othandekayo wakho nibhekene nenselele yomdlavuza wamaphaphu ongeyena omncane oguquliwe we-KRAS G12C, sicela ukhululeke ukuxhumana ne-International Department of Beijing South Region Oncology Hospital. Ithimba lethu lochwepheshe lizokunikeza ukubonisana okuningiliziwe kwezokwelapha kanye nosizo lokufuna ukunakekelwa kwezokwelapha eShayina.
- Ukubonisana Ngocingo: 400-880-3716
- Ukubonisana kwe-WeChat: 17801183037
- I-imeyili:
- 100085_010@163.com
- myimmnet@163.com
**Imibuzo ejwayelekile ukubuzwa**
**U: Iziguli zakwamanye amazwe zingazihlela kanjani izinsizakalo zezokwelapha eMnyangweni Wezangaphandle Wesibhedlela i-Beijing South Region Oncology?**
**Impendulo:** Ungasithinta ngocingo, i-WeChat, noma i-imeyili. Abaxhumanisi bethu beziguli bamazwe ngamazwe bazokuqondisa ngenqubo yokuqokwa, okuhlanganisa ukuthunyelwa kwamarekhodi ezokwelapha, ilungiselelo lokubonisana kude, kanye nosizo lwe-visa lokuya eShayina.
**U: Ziyini izindleko zeziguli zamazwe ngamazwe ezithola ukwelashwa eShayina?**
**Impendulo:** Izindleko zokwelashwa ziyahlukahluka kuye ngezimo zomuntu ngamunye, okuhlanganisa nohlelo lwemithi kanye nobude besikhathi sokwelashwa. Ngemva kokuxhumana nathi, sizokunikeza isilinganiso sezindleko esinemininingwane ngokusekelwe esimweni sakho esithile.
**U: Ingabe isibhedlela sihlinzeka ngezinsizakalo zokubonisana nabantu sikude?**
**Impendulo:** Yebo, sinikeza izinsizakalo zokubonisana ngevidiyo ezikude zeziguli zakwamanye amazwe, okukuvumela ukuthi ube nengxoxo yokuqala nethimba lethu lochwepheshe ngaphambi kokuya eShayina ukuze uqonde uhlelo lokwelashwa kanye nemiphumela elindelekile.
Isikhathi sokuthunyelwe: Mashi-04-2026