Muva nje, i-National Medical Products Administration yaseShayina ivumile ngokusemthethweni ukwelashwa okuhlanganisiwe kwe-Anlotinib Hydrochloride kanye ne-Penpulimab yi-Chia Tai Tianqing ekwelapheni kokuqala kwe-carcinoma ye-hepatocellular ethuthukisiwe. Lokhu kuphawula isibonakaliso seshumi esivunyelwe se-Anlotinib Hydrochloride, okubonisa inketho ebalulekile entsha emkhakheni wokwelashwa komdlavuza wesibindi othuthukisiwe. Lokhu kwelashwa kusekelwe ocwaningweni lwezokwelapha lweSigaba III olushicilelwe kumagazini we-oncology odumile emhlabeni wonke *The Lancet Oncology*, onedatha yalo yokusebenza ephawulekayo eletha ithemba elisha ezigulini emhlabeni jikelele.
**Intuthuko Yocwaningo: Kukhulisa Kakhulu Ukusinda Futhi Kunciphisa Ingozi Yezifo**
Lolu cwaningo, olubizwa ngokuthi i-ALTN-AK105-III-02, luyisilingo sezokwelapha seSigaba III esinama-centre amaningi, esingahleliwe, esivulekile, esilawulwa ngokulinganayo esenzelwe ukuhlola ukusebenza kwe-Anlotinib Hydrochloride ehlanganiswe ne-Penpulimab uma kuqhathaniswa nomuthi ojwayelekile wendabuko i-Sorafenib ekwelashweni kokuqala kwe-carcinoma yesibindi ethuthukisiwe. Lolu cwaningo lubhalise iziguli ezingu-649 ezinomdlavuza wesibindi othuthukisiwe, cishe ezingu-41% zazo zazinokuhlasela kwemithambo yegazi, kanti cishe ezingu-49.2% zazinamazinga aphezulu e-alpha-fetoprotein (≥400 ng/mL). Lezi zici ngokuvamile zibonisa izinselele ezinkulu zokwelapha.
Imiphumela yocwaningo iyakhuthaza:
- **Ukwelulwa Okubalulekile Kokusinda Okungenalo Inqubekelaphambili:** Isikhathi esimaphakathi sokusinda okungenalo inqubekela phambili eqenjini lokwelapha elihlanganisiwe sifinyelele ezinyangeni ezingu-6.9, sidlula kakhulu izinyanga ezingu-2.8 eqenjini lokulawula, kanye nokwehla okungu-47% kwengozi yokuqhubeka kwesifo noma ukufa.
- **Intuthuko Ephawulekayo Ekusindeni Konke:** Ukusinda okumaphakathi okuphelele eqenjini lokwelashwa okuhlanganisiwe bekuyizinyanga ezingu-16.5, uma kuqhathaniswa nezinyanga ezingu-13.2 eqenjini lokulawula, okumele ukwehla okungu-31% kwengozi yokufa.
Le datha "emibili emihle" ayibonisi nje kuphela izinzuzo zalolu hlobo lokwelapha ekubambezeleni ukuqhubeka kwesifo kodwa futhi ikhombisa impumelelo enkulu ezinzuzweni zokusinda zizonke, inikeza izinketho zokwelapha ezisebenza kahle kakhulu ezigulini ezinomdlavuza wesibindi othuthukile.
**UMnyango Wezizwe Ngezizwe Wesibhedlela Se-Oncology saseBeijing South Region: Umlingani Wakho Womhlaba Wonke Wokulwa Nomdlavuza**
Uma ubhekene nomdlavuza, ukufinyelela ngesikhathi kolwazi lwezokwelapha olugunyaziwe kanye nokusekelwa kokwelashwa kochwepheshe kubalulekile. UMnyango Wezizwe Ngezizwe Wesibhedlela i-Beijing South Region Oncology uzinikele ekuhlinzekeni ngezinsizakalo eziphelele zokuxilongwa kwe-oncology kanye nokwelashwa kweziguli zamazwe ngamazwe, okuhlanganisa ukubonisana ngezokwelapha zakamuva, ukuhlela ukwelashwa komuntu siqu, kanye nosizo lokuxhumana ngolimi oluhlukile. Sisebenzisana eduze nezikhungo zocwaningo zasekhaya nezamazwe ngamazwe ukuqinisekisa ukuthi iziguli ziyazuza ekuthuthukisweni okuphambili njengokwelashwa okuhlanganisiwe kwe-Anlotinib Hydrochloride.
**Ulwazi Lokuxhumana: Silapha Ukuzokukhonza**
Uma wena noma abathandekayo bakho nifuna izindlela zokwelapha umdlavuza wesibindi othuthukile noma ezinye izimila, sicela usithinte ngokushesha ngezindlela ezilandelayo. Ithimba lethu lochwepheshe lizohlinzeka ngezingeniso zokwelapha ezinemininingwane, isiqondiso senqubo yezokwelapha, kanye nokusekelwa kweziguli zomhlaba wonke:
- **Ucingo:** 400-880-3716
Shayela le nombolo ukuze ukhulume ngqo nabaxhumanisi bethu beziguli bamazwe ngamazwe ukuze uthole izeluleko ezisheshayo kanye nosizo lokuqokwa.
- **WeChat:** 17801183037
Engeza i-akhawunti yethu esemthethweni ye-WeChat ukuze uthole ulwazi lokwelashwa ngesikhathi sangempela, imibuzo eku-inthanethi, noma ukubonisana ngevidiyo.
- **I-imeyili:**
① 100085_010@163.com
② myimmnet@163.com
Thumela amarekhodi ezokwelapha noma imibuzo ku-imeyili yethu, futhi ithimba lethu lochwepheshe lizonikeza izincomo zokwelapha ezenzelwe wena.
**Kungani Sikhethe?**
- **Ukufinyelela Ekwelashweni Okusezingeni Eliphezulu:** Silandela njalo izitayela zokwelapha umdlavuza emhlabeni jikelele ukuqinisekisa ukuthi iziguli zinethuba lokuthola izixazululo ezintsha njengokwelashwa okuhlanganisiwe kwe-Anlotinib Hydrochloride.
- **Izinsizakalo Ezinezilimi Eziningi:** Sinikeza ukwesekwa ngezilimi eziningi, okuhlanganisa nesiNgisi, ukuze siqede izithiyo zokuxhumana futhi siqinisekise ukuthi iziguli zakwamanye amazwe zinolwazi olungenamthungo.
- **Usizo Oluphelele:** Kusukela ekufakweni kwezicelo ze-visa kanye namalungiselelo okuhlala kuya ekulandelelweni kokwelashwa, sinikeza izinsizakalo zokunaka ezifika kanye kuphela.
Ukwelashwa komdlavuza kuwumjaho ohambisana nesikhathi. Ukuvunyelwa kokwelashwa okuhlanganisiwe kwe-Anlotinib Hydrochloride kulethe ithemba elisha ezigulini ezinomdlavuza wesibindi othuthukile. Kungakhathaliseki ukuthi ukuphi, uMnyango Wezempilo Wesibhedlela Samazwe Ngamazwe saseBeijing South Region Oncology usukulungele ukuba ngumlingani wakho oqinile ohambweni lwakho lokulwa nomdlavuza. Xhumana nathi namuhla ukuze uqale uhambo lwakho lokwelashwa oluqondene nawe!
**Khumbula Ulwazi Lwethu Lokuxhumana:**
Ucingo: 400-880-3716
I-WeChat: 17801183037
Email: 100085_010@163.com or myimmnet@163.com
Silangazelela ukukunikeza ukwesekwa kwezokwelapha kochwepheshe nozwela!
Isikhathi sokuthunyelwe: Jan-27-2026