Ngomhlaka-9 kuNhlolanja 2026, iwebhusayithi esemthethweni ye-Center for Drug Evaluation (CDE) ye-National Medical Products Administration (NMPA) yamemezela ukuthi i-ZL-1310 yokujova, i-DLL3-targeting antibody-drug conjugate (ADC) entsha, ihlelwe ukuthi inikezwe i-Breakthrough Therapy Designation.
Njengelungu lePeking University Cancer Hospital Medical Consortium kanye nesibhedlela sesimanje esikhethekile se-Beijing secondary modern oncology, uMnyango Wezizwe Ngezizwe weBeijing South Region Oncology Hospital usebenzisa ipulatifomu enamandla yokuxilonga kanye nokwelashwa ukuze uhlanganise ngokushesha izindlela zokwelapha eziholayo emhlabeni wonke ezinhlelweni zokwelapha iziguli zamazwe ngamazwe. Uma wena noma othandekayo wakho ubhekene nezinselele zokwelashwa komugqa wesibili noma kamuva komdlavuza wamaphaphu wamaseli amancane, sicela ufunde ngokucophelela idatha engezansi bese usithinta ngokushesha.
Xhumana noMnyango Wezizwe Wesibhedlela i-Beijing South Region Oncology Hospital manje:
- Ucingo: 400-880-3716
- I-ID ye-WeChat: 17801183037
- Email ①: 100085_010@163.com
- Email ②: myimmnet@163.com
**Idatha Eqinile: Kufika ku-86% Ukusebenza Kahle Ezigulini Ezine-Brain Metastases**
Emhlanganweni Waminyaka Yonke we-American Society of Clinical Oncology (ASCO) ka-2025, kwethulwe idatha yesifundo somtholampilo sesigaba 1a/1b somhlaba wonke se-ZL-1310.
Kweziguli ezelashwe ngaphambilini (ukwelashwa komugqa wesibili):
- Izinga lokuphendula okuqondile elingakaqinisekiswa (uORR) lifinyelele ku-67%, kanti izinga lokulawula izifo (DCR) lingu-97%.
- Eqenjini lesilinganiso sebhayoloji esingcono kakhulu (1.6 mg/kg): Izinga lokuphendula eliqondile (ORR) lenyuke laya ku-79%, kanti izinga lokulawula izifo (DCR) lingu-100%.
- Lokhu kusho ukuthi: Cishe zonke iziguli eziyi-10 ezithola lo mthamo zifinyelele ekulawulweni kwesimila, kanti cishe iziguli eziyi-8 zancipha kakhulu isimila.
Iziguli eziyinselele kakhulu ezine-metastases yobuchopho:
- Iziguli ezine-metastases yobuchopho obuyisisekelo: Izinga lokuphendula okuqondile (ORR) lalingu-68%.
- Iziguli ezingakaze zithole ukwelashwa ngemisebe yekhanda: Izinga lokuphendula okuqondile (ORR) laliphezulu lifinyelela ku-86%!
Lolu lwazi luyinto entsha. Imithi yendabuko yamakhemikhali iyahluleka ukungena emgomweni wegazi nobuchopho, kodwa i-ZL-1310 ikhombisa ukusebenza okuqinile kokulwa nomdlavuza ngaphakathi kwekhanda. Ezigulini zamazwe ngamazwe ezikhathazekile ngemiphumela emibi yokwelashwa ngemisebe yobuchopho bonke, lokhu kumelela ithemba elikhulu "lokugwema imisebe yobuchopho."
**Iphrofayili Yokuphepha:** Eqenjini lomthamo elingaphansi kuka-2.0 mg/kg, izehlakalo zezehlakalo ezimbi ezihlobene nokwelashwa (ama-TRAE) zebanga lesi-3 noma ngaphezulu zaziyi-6% kuphela, kungekho mibiko yezehlakalo zesifo samaphaphu esihlobene nokwelashwa (ILD) noma zokuyekiswa kokwelashwa.
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**III. Kungani Ukhethe UMnyango Wezizwe Ngezizwe Wesibhedlela Se-Oncology SaseBeijing South Region?**
Ezigulini zamazwe ngamazwe, ukuthola izindlela ezintsha zokwelapha akukhona nje ukuthi “umuthi uyatholakala yini,” kodwa futhi kuyinqubo ehlelekile ehilela “ubani ongawusebenzisa, ukuthi uwusebenzisa kanjani, nokuthi ubani olawula imiphumela emibi.”
UMnyango Wezizwe Ngezizwe Wesibhedlela i-Beijing South Region Oncology uhlinzeka ngokuhlolwa okuzayo kanye nokuphathwa komjikelezo ogcwele wezindlela zokwelapha ezisezingeni eliphezulu njenge-ZL-1310 zeziguli ezifanelekile. Kungakhathaliseki ukuthi uvela eNingizimu-mpumalanga ye-Asia, eMpumalanga Ephakathi, eYurophu, noma eMelika, sinenqubo yenkonzo yezokwelapha yamazwe ngamazwe esemisiwe.
Sinikeza izinsizakalo eziphelele kusukela ekubonisaneni ngaphambi kokuya esibhedlela, ukuhumusha ngezilimi eziningi, izincwadi ze-visa yezokwelapha, kuya ekulandeleni ukwelashwa. Ukunamathela ngokuqinile enqubomgomo ethi “udokotela oyedwa, isiguli esisodwa, igumbi elilodwa” kuqinisekisa ukuthi ubumfihlo bakho nesithunzi sakho kuyahlonishwa ngokugcwele, ngisho nakwelinye izwe.
Njengamanje, i-ZL-1310 inikezwe i-Orphan Drug Exposure kanye ne-Fast Track Exposure yi-US FDA. Ukufakwa kwayo okuhleliwe ku-Breakthrough Therapy Declaration yaseShayina kuzosheshisa kakhulu ukutholakala kwayo eShayina.
Ungavumeli izithiyo zolimi, izikhala zolwazi, noma izinqubo ezinzima zikuvimbele ekutholeni ukwelashwa okuthuthukile. UMnyango Wezangaphandle Wesibhedlela SaseBeijing South Region Oncology usungule umzila oluhlaza weziguli zakwamanye amazwe.
Thatha ucingo noma usithinte nge-WeChat noma i-imeyili ukuze wabelane ngesimo sakho. Abeluleki bethu bezokwelapha bazokunikeza ukuhlolwa kokuqala zingakapheli amahora angama-24.
- Ucingo (ukubonisana amahora angama-24): 400-880-3716
- I-WeChat (ukuxhumana okusheshayo): 17801183037 (isekela isiNgisi nesiShayina)
- I-imeyili (yamarekhodi ezokwelapha):
- 100085_010@163.com
- myimmnet@163.com
Isikhathi sokuthunyelwe: Feb-12-2026