Muva nje, i-Center for Drug Evaluation (CDE) ye-China National Medical Products Administration ivumile ngokusemthethweni umjovo we-KSD-101, owakhiwe nguKousai, ukuze ungene ezivivinyweni zemitholampilo. Lokhu akugcini nje ngokugomela kokuqala kwe-dendritic cell (umuthi wokugomela we-DC) eShayina ukuthola imvume ye-FDA IND kodwa futhi kungowokuqala wohlobo lwawo eShayina ukunikezwa i-Fast Track Designation (FTD) yi-US Food and Drug Administration. Lesi sigameko sisho inkathi entsha yokwelashwa nge-immunotherapy komuntu siqu kwama-tumor e-hematologic ahlobene ne-EBV.
I-KSD-101 iwumuthi wokugomela we-DC wokuqala owenziwe yi-Kousai Biotechnology ngokusekelwe epulatifomu yayo yobuchwepheshe ethi “Eco-DC Vax” ezenzele yona, futhi iwumkhiqizo wokuqala wokugomela we-DC eShayina ukuthola imvume ye-FDA IND. Indlela esebenza ngayo ihilela ukulungiselela umuthi wokugomela owenzelwe umuntu ngamunye ngokuqoqa amaseli e-mononuclear esiguli, ukuwabangela ukuba ahluke abe amaseli e-dendritic in vitro, bese ewalayisha ngama-antigen ayinkimbinkimbi ahlobene ne-EBV. Ngemva kokuba umuthi wokugomela usubuyiselwe emzimbeni wesiguli, ungasebenza futhi uqeqeshe ngokunembile amasosha omzimba esiguli ukuthi aqaphele futhi abulale amaseli esimila aveza ama-antigen e-EBV, ngenkathi esungula inkumbulo yomzimba yokulwa nesimila ehlala isikhathi eside.
### Imininingwane Yezokwelapha Ehlaba Umxhwele: Ubufakazi Bokuqala Bokuphepha Nokusebenza Kahle
Amandla e-KSD-101 aqinisekiswe ekuqaleni ezifundweni zokwelapha zangaphambilini. Esifundweni sezokwelapha seSigaba I se-KSD-101 njengendlela yokwelapha kuphela izimila zegazi ezihambisana ne-EBV eziphinde zaphindeka futhi ezingalapheki, izinga lokuphendula eliqondile (ORR) lifinyelele phezulu ku-91.67%, ngesilinganiso sokukhululwa okuphelele (CR) esingu-83.33% kanye nesilinganiso sokulawula izifo (DCR) esingu-100%. Ukwelashwa kubonise nezimpendulo ezihlala isikhathi eside kanye nephrofayili yokuphepha enhle. Le datha entsha inikeza ukwesekwa okuqinile kwenani lomtholampilo le-KSD-101.
### Kungani Kufanele Ukhethe iShayina Yezokwelapha Ezisezingeni Eliphezulu?
IShayina ithuthuka ngokushesha ocwaningweni lwezokwelapha kanye nokusetshenziswa kwemikhakha esezingeni eliphezulu njengokwelashwa ngamaseli kanye nokwelashwa ngemithi yokuzivikela komzimba. UMnyango Wezwe Lonke Wesibhedlela Se-Oncology SaseBeijing South Region uzinikele ekuxhumeni iziguli zomhlaba wonke nobuchwepheshe bezokwelapha bamuva kanye namathuba okuhlolwa kwezokwelapha. Intuthuko esheshayo ye-KSD-101 eShayina isho ukuthi iziguli zomhlaba wonke zingase zibe nokufinyelela kwangaphambi kwesikhathi kulolu hlobo lokwelapha olushintshayo.
### Xhumana Nathi Ukuze Uthole Ulwazi Olwengeziwe noma Ukuhlola Ukufaneleka
Uma wena noma othandekayo wakho nithintekile yizimila zegazi ezihlobene ne-EBV (njenge-lymphoma refractory to standard treatment noma i-CAEBV) futhi ninesithakazelo ekwelashweni okuphumelelayo kwe-KSD-101, sikumema ngobuqotho ukuthi uxhumane ne-International Department of Beijing South Region Oncology Hospital. Ithimba lethu lezokwelapha lamazwe ngamazwe lizohlinzeka ngezeluleko zobungcweti, ukuhlolwa kwamarekhodi ezokwelapha, futhi lisize ekunqumeni ukufaneleka kokubamba iqhaza ezivivinyweni zezokwelapha ezizayo.
Sicela usithinte ngokushesha ngalezi ziteshi ezilandelayo:
Ucingo: 400-880-3716
I-WeChat: 17801183037
Email: 100085_010@163.com | myimmnet@163.com (backup)
Siyaqonda ukuthi wonke amathuba okwelashwa ayindaba yokuphila nethemba. UMnyango Wezwe Lonke Wesibhedlela Se-Oncology SaseNingizimu Yesifunda saseBeijing uzibophezele ekuvaleni igebe phakathi kweziguli nobuchwepheshe bezokwelapha obusezingeni eliphezulu ngobuchwepheshe bochwepheshe kanye nokunakekelwa okunesihawu. Masibheke phambili futhi sisebenzisane ukuze sinqobe lesi sifo.
**UMnyango Wezizwe Ngezizwe Wesibhedlela Se-Oncology saseBeijing South Region**
Ucingo: 400-880-3716
I-WeChat: 17801183037
Email: 100085_010@163.com / myimmnet@163.com
Isikhathi sokuthunyelwe: Mashi-17-2026