KwaPuhua, ubuchwepheshe obuhamba phambili bokwelapha umdlavuza buhlanganiswa nokwelashwa kwemvelo ukukusiza ukulwa nalesi sifo nokugcina ikhwalithi yempilo yakho.
Ukwelashwa Komdlavuza Okunemikhakha Ehlukahlukene
Ukwelashwa Komdlavuza
Isibhedlela Samazwe Ngamazwe saseBeijing Puhua sisebenzisa ubuchwepheshe obuhamba phambili ukwelapha umdlavuza ngamandla. KwaPuhua, ubuchwepheshe obuhamba phambili bokwelapha umdlavuza buhlanganiswa nokwelashwa kwemvelo ukukusiza ukulwa nalesi sifo nokugcina ikhwalithi yempilo yakho.
Umgomo kaPuhua:
·Ithimba lochwepheshe bemikhakha eminingi
·Uhlelo lokwelashwa oluqondene nawe, oluphelele
·Izindlela zokwelapha ezisabelayo ukuze zivumelane nesigaba sesimila
·Nciphisa imiphumela emibi
·Thuthukisa ikhwalithi yokuphila kwesiguli iyonke
Izindlela zokwelapha ezitholakala ePuhua
Ukususwa Kwemisebe Yemisebe
Ngokusebenzisa ubuchwepheshe be-Ultrasound kanye ne-CT, siyakwazi ukufaka ngqo izinaliti ezikhiqiza ukushisa enkabeni yendawo yomdlavuza. Indawo iyafudunyezwa bese kuthi uma isidlule ku-60℃, ukuwohloka okuhlelekile kwamaprotheni emaseli omdlavuza kuzokwenzeka kuze kube yilapho eba yingozi.
Ukususwa Kwe-Cryosurgical (CSA)
Kusetshenziswa amasu aqondiswa yizithombe (i-Ultrasound, i-CT noma i-MRI), ama-cryo-probe afakwa ezinhlamvini ukuze kwehliswe izinga lokushisa lendawo eqondiwe -160℃ noma ngaphansi. Kamuva izinga lokushisa liphakanyiswa phakathi kuka-20 kuya ku-40℃. Le nqubo iphindaphindwa kabili noma kathathu, okuholela ekususweni ngokuphelele kwesimila.
I-CSA inezinzuzo ezilandelayo:
• Isebenza kokubili ezimila ezincane nezinkulu. Ingasetshenziswa ekususeni izimila ezimilayo eyodwa noma eziningi.
• Ukuhlinzwa okuhlinzayo ngeke kubangele umonakalo emithanjeni yegazi emikhulu kanye nase-trachea, ngakho-ke kungasetshenziswa ukwelapha izimila eduze kwalezo zindawo.
• Kuwukuhlinzwa okungenabuhlungu, futhi kusiza ekunciphiseni ubuhlungu obubangelwa umdlavuza.
• Yonke inqubo yokususwa kwezicubu ezicryus ingaqashwa ngokusebenzisa amasu okuthwebula izithombe njenge-ultrasound, i-CT noma i-MRI.
• Ngemva kokuba amangqamuzana anomdlavuza ebhujiswe yi-CSA, amangqamuzana anomdlavuza afile azokhipha ama-antigen azokhuthaza amasosha omzimba ukuba aqede noma yimaphi amangqamuzana anomdlavuza asele futhi anciphise ukuphindeka komdlavuza.
Ukungenelela Kwemithambo Yegazi Emincane Yomdlavuza (i-CMI)
Ngokufaka i-catheter emithanjeni eqondiwe kanye nokufaka izinto zokufaka i-embolic, ama-chemotherapy noma imithi yendabuko yaseShayina siyakwazi ukubangela ukulahlekelwa igazi emaseli omdlavuza okuholela ekuqhekekeni kwezicubu zesimila nge-ischemia. Ngokwenza lokhu siyakwazi ukubulala umdlavuza ngendlala.
Ukwelashwa Nge-NanoKnife
Yaziwa nangokuthi i-Irreversible Electroporation (IRE). Isizathu sayo sihamba kanje: ngesikhathi senqubo, kunikezwa ama-electro-field aphezulu kanye nama-pulse amafushane kakhulu ukuze kubhujiswe isakhiwo se-lipid bilayer ye-cancer cell membrane futhi kwakhiwe ama-nano-size pores amaningi angaguquki ku-cell membrane. Ukungena kwe-cell membrane kuzoshintshwa ukuze kuvunyelwe ama-molecule anobukhulu obuhlukene ukufinyelela mahhala kumaseli, okuzoholela ekufeni kweseli.
Ukwelashwa nge-Nanoknife kungasetshenziswa ekwelapheni izimila ezithweni eziqinile njenge-pancreas, isibindi, amaphaphu, izinso kanye ne-prostate, futhi kufaneleka kakhulu ezimila eziseduze ne-pancreas, isifunda se-hepatic hilar, i-gallbladder, i-bile duct kanye ne-ureters.
Ukwelashwa Nge-Photodynamic (PDT)
(ngezinye izikhathi okubizwa ngokuthi i-photo-chemotherapy), uhlobo lwe-phototherapy olusebenzisa amakhemikhali angenabo ubuthi azwela ekukhanyeni abonakala kumaza okukhanya akhethiwe, lapho eba asebenzayo futhi abe nobuthi ezicutshini eziyingozi eziqondiwe kanye nezinye izicubu eziqondiwe. I-PDT ifakazelwe ukuthi ibulala amagciwane, isikhunta kanye namagciwane, futhi isetshenziswa kakhulu ekwelapheni induna. Isetshenziswa ngokwezokwelapha ukwelapha izifo eziningi zezokwelapha, okuhlanganisa ukuwohloka kwe-macular okuhlobene nobudala okumanzi (i-AMD) kanye nomdlavuza onobungozi, futhi ibhekwa njengesu lokwelapha eliphumelelayo nelikhethayo elingangenisi kakhulu futhi elingabuthi kakhulu.
Ukwelashwa nge-Immunotherapy (ukwelashwa nge-DC-CIK)
Ukwelashwa nge-CIK (amangqamuzana okubulala abangelwa yi-cytokine): Amangqamuzana e-CIK angama-T-Cell anobuthi angafuna futhi abulale amangqamuzana esimila. Inani lamangqamuzana e-CIK akhona emzimbeni lincane kakhulu, futhi alanele ukulwa nomdlavuza. Ekwelashweni nge-CIK, amangqamuzana e-CIK ayahlukaniswa, akhuliswe okungenani izikhathi eziyi-1,000, bese ephinde afakwe emzimbeni wesiguli.
Ukushisa okuphezulu:
Ukuhlolwa kubonisa ukuthi amandla okupholisa amaseli esimila aphansi kakhulu kunalawo amaseli avamile. Uma izinga lokushisa lifinyelela ku-42.5 ℃ futhi lihlala imizuzu engaphezu kwengu-30, amaseli esimila azoshisa ngokushesha futhi abangele ukulimala, ukuwohloka kanye ne-necrosis. Kodwa-ke, amaseli aphilile angagwema umonakalo ngokusebenzisa indlela enhle yokupholisa. I-Thermotron-RF8 ingumshini wakamuva we-hyperthermia othuthukiswe eJapane, ongabeka kahle isimila futhi wenze i-hyperthermia. Nakuba inciphisa ivolumu yesimila futhi inciphise ubuhlungu, ingavimbela ukuphindaphinda komdlavuza futhi ithuthukise imiphumela yezinye izindlela zokwelapha.
Ukwelashwa Ngezifo Ezingalawuleki Kwe-PD-1:
I-PD-1/PD-L1: I-PD-1 uhlobo olulodwa lwe-receptor yeseli le-T esebenzayo. I-microenvironment yesimila sangaphakathi izobangela i-molecule ye-PD-1 eveza i-T-cell ephezulu, iseli lesimila lizoveza i-ligands ye-PD-1 (PD-L1 kanye ne-PD-L2), okuyindlela ehamba phambili ye-PD-1 eqhubeke nokusebenza endaweni encane yesimila. Ngemva kokuxhumana kwe-PD-L1 ne-PD-1, umsebenzi weseli le-T uzovinjelwa, futhi ungakwazi ukuthumela izimpawu ezihlasela isimila ohlelweni lokuzivikela komzimba. I-PD-1/ PD-L1 inhibitor ingavimba ukuxhumana kwe-PD-1 kanye ne-PD-L1, futhi ivimbele izimpawu zokulawula ezingezinhle ukuze ibuyisele ukusebenza kweseli le-T, bese ithuthukisa impendulo yomzimba. I-PD-1 kanye ne-PD-L1 inhibitor inethonya elikhulu ekwelashweni okuhlukahlukene komdlavuza.
Imithi Yendabuko YamaShayina (i-TCM)
I-TCM iyindlela yokwelapha ephephile nephumelelayo esetshenziswa kanye nezinye izindlela zokwelapha. Amakhambi amaningi aseShayina anemiphumela enamandla yokuthuthukisa amasosha omzimba, futhi angathuthukisa imiphumela ye-chemotherapy, ukwelashwa ngemisebe, ukuhlinzwa, kanye nezinye izindlela ngenkathi enciphisa ubuthi kanye nemiphumela emibi. Amakhambi endabuko aseShayina anganikezwa ngomlomo, ngokufaka i-IV, noma ngokujova emithanjeni yokondla isimila ngosizo lwe-DSA (i-digital subtraction angiography)
isiqondiso.
Ithimba Lezokwelapha Eziningi Ezifundisayo
UDkt. Xue Zhongqi—Umqondisi we-Oncology, Udokotela Ohlinzayo Oyinhloko We-Oncology
UDkt. Xue uletha eBeijing Puhua International Hospital imiphumela yeminyaka engaphezu kwamashumi amathathu (30) yesipiliyoni sezokwelapha njengomunye wodokotela abahlinzayo abaphambili bomdlavuza eShayina. Unguchwepheshe oholayo negunya ekuxilongeni nasekwelapheni izinhlobo ezahlukene zomdlavuza. Uyaziwa ngomsebenzi wakhe kumdlavuza webele, ikakhulukazi ezindaweni zokususwa kwebele kanye nokwakhiwa kabusha kwamabele.
UDkt. Xue wenze ucwaningo olujulile kanye nocwaningo lwezokwelapha ezindaweni ezifana nomdlavuza we-colonectal, i-sarcoma, umdlavuza wesibindi kanye nomdlavuza wezinso, futhi ushicilele amaphepha nezihloko zezemfundo ezingaphezu kwamashumi amabili (20) ezinkulu (kokubili ucwaningo oluyisisekelo kanye nolwezokwelapha) ngalezi zindawo zezokwelapha. Eziningi zalezi zincwadi zizuze imiklomelo eyahlukahlukene emihle.
UDkt. Zhao Yuliang—Umqondisi Ohlangene We-Oncology, Udokotela Oyinhloko We-Oncologist
UDkt. Zhao unolwazi oluhlukile, ukuqeqeshwa kanye nolwazi mayelana nokuphathwa kwezokwelapha kweziguli ze-oncology kanye nokuphathwa kwezokwelapha kanye nokwelashwa kwamacala omdlavuza ayinkimbinkimbi.
UDkt. Zhao unekhono elikhulu ekunciphiseni imiphumela emibi engaba khona esigulini ngenxa yokwelashwa ngamakhemikhali. Ezama njalo ukuthuthukisa izintshisekelo ezinhle kanye nenduduzo yeziguli ezisebenzisa amakhemikhali, ngesikhathi esifanayo ezama ukuthuthukisa ikhwalithi yempilo yazo, uDkt. Zhao usebe ngummeli ohamba phambili wokuthuthukisa uhlelo lokwelapha oluphelele nolugxile esigulini ngasinye lomdlavuza wesiguli ngasinye.
UDkt. Zhao usebenza ohlelweni oluhlanganisiwe lwe-oncology eBeijing Puhua International Hospital, lapho esebenza khona ngokubambisana ne-oncology yokuhlinzwa, imithi yendabuko yaseShayina, kanye nokwelashwa ngamasosha omzimba ukuze kuthuthukiswe imiphumela yezokwelapha yesiguli ngasinye.
UDkt. Allen (Yuansen) Gao
UDkt. Allen Gao ungudokotela we-TCM owaphothula eLiaoning University of Traditional Chinese Medicine. Wafunda ngaphansi kukaSolwazi Ligong Xue owaziwa ngocwaningo lwakhe lwezifo ze-meridian-tendon e-Acupuncture Institute of the Chinese Academy of Sciences kanye neLondon Application Technology Research Institute. Usebenzise ucwaningo lwezokwelapha lwe-meridian-tendon kakhulu, futhi unolwazi olunzulu locwaningo kanye nokwelashwa ezindleleni kanye nokwelashwa kobuhlungu, kanye nezifo zemisipha. Unolwazi olucebile lwezokwelapha ngokusebenzisa i-acupuncture ezinhlotsheni eziningi zezifo zemizwa, i-intervertebral disc herniation, isifo sikashukela kanye nobuhlungu obungapheli. UDkt. Allen Gao usebenzisa ubuchwepheshe be-TCM futhi ubuhlanganisa nemithi nezindlela zesimanje zaseNtshonalanga. Unedumela elihle ekwelapheni izifo zemizwa kanye nomgogodla.